Alzheimer's Disease - Saccadic Eye Movements

Inhibitory Control of Saccadic Eye Movements and Cognitive Impairment in Alzheimer’s Disease

Background

This study examined the relationship of inhibitory control and measures of neuropsychological impairment in patients with early Alzheimer’s disease (AD). Four specific questions were addressed:

1) Which error parameters of saccadic inhibition are sensitive to AD?

2) Which inhibitory deficits are related to cognitive measures of impairment?

3) Is the inhibitory impairment in AD dependent on the initiation of a volitional eye movement?

4) How do the effects of saccadic inhibitory control in AD relate to the normal effects of aging?

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